If you do not have Visual C++ 2010 Runtime installed on your Windows PC you will need to run this installer before installing DeSmuME as it depends on the DLLs from the Visual C++. NDeSmuME Version 0.9.11 (x86) 32-bit for Older PCs with Windows 10 32-bit Version, Windows 7 and WinXP
NDeSmuME Version 0.9.11 (圆4) 64-bit for Windows 10, Vista and Windows 7